Use of Fibroblast Growth Factor 2 for Expansion of Chondrocytes and Tissue Engineering

31, pp. 273-280, 1996.* Quarto, et al., “Proliferation and Differentiation of Chondrocytes in Defined Culture Medium: Effects of Systemic Factors”, Bone: 17(6) 588, 1995. Quarto, et al., “Modulation of Commitment, Proliferation, and Differentiation of Chondrogenic Cells in Defined Culture Medium”, Endocrinology, 138: 4966-4976, 1997. Yaeger, et al., “Synergistic Action of Transforming Growth Factor-fl and Insulin-Like Growth Factor-1 Induces Expression of Type I1 Collagen and Aggrecan Genes in Adult Human Articular Chondrocytes”, Experimental Cell Research:237: 318-325, 1997. Freed et al., “Joint Resurfacing Using Allograft Chondrocytes and Synthetic Biodegradable Polymer Scaffolds” Biomed. Mat. Res., 28391-899, 1994. Kat0 et al., “Sulfated Proteoglycan Synthesis by Confluent Cultures of Rabbit Costal Chondrocytes Grown in the Presence of Fibroblast Growth Factor” J. Cell Biol., 100(2):477-485, Feb. 1985. Kat0 et al., “Fibroblast Growth Factor is an Inhibitor of Chondrocyte Terminal Differentiation” J. Biol. Chem., 265(10):5903-5909, 1990. Langer et al., “Tissue Engineering” Science, 260: 920-926, May 14, 1993. Langer et al., “Future Directions in Biomaterials” Biomaterials, 11:738-745, 1990. Minas et al., “Current Concepts in the Treatment ofArticular Cartilage Defects” Orthopedics, 20(6): 525-538, Jun. 1997. Rheinwald et al., “Serial Cultivation of Strains of Human Epidermal Keratinocytes: the Formation of Keratinizing Colonies from Single Cells” Cell, 6:331-344, Nov. 1975. Toolan et al., “Effects of Growth-Factor-Enhanced Culture on a Chondrocyte-Collagen Implant for Cartilage Repair” Biomed Mater Res., 31(2):273-280, Jun. 1996. Vacanti et al., “Selective Cell Transplantation Using Bioabsorbable Artificial Polymers as Matrices” J. Pediatr: Surg., 23(1):3-9, Jan. 1988. Vacanti et al., “Beyond Transplantation” Arch. Surg., 123:545-549, May 1988.